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CA2730603A1 Agonists of guanylate cyclase useful for the

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Pharmacological rationale for the use of somatostatin and analogues in portal hypertensi

phosphoinositide 3-kinase and guanylate cyclase) responsible for the synthesis or degradation of intra-cellular second messengers including cyclic AMP, ...

Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colit

Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis ...

PHAR222 Flashcards | Quizl

-agonists of peroxisome proliferator-activated ɑ receptors (PPAR ɑ)-activates PPAR ɑ - ligand gated transcription factors ... -activation of guanylate cyclase-↑ cGMP-activate SR Ca++ pump to reduce cytoplasmic Ca++-inhibits Ca++ channels - ↓ Ca++ influx into ...

Effects of In Vivo Nitroglycerin Treatment on Activity and Expression of the Guanylyl Cyclase and cGMP-Dependent Protein Kinase and Their .

Effects of In Vivo Nitroglycerin Treatment on Activity and Expression of the Guanylyl Cyclase and cGMP-Dependent Protein Kinase and Their Downstream Target Vasodilator-Stimulated Phosphoprotein in Aorta Alexander Mülsch, Matthias Oelze, Stefan Klöss,

Christopher Joseph Sinz Inventions, Patents and Patent Applications - Justia Patents Sear

Abstract: This inventions relates to compounds having the structure Formula I and pharmaceutically acceptable salts thereof which are soluble guanylate cyclase activators. The compounds are useful for treatment or prevention of cardiovascular diseases ...

Pulmonary Hypertension Part 2 - YouTu

In this video we discuss the pathophysiology of Pulmonary Arterial Hypertension, along with how the soluble Guanylate Cyclase activator Riociguat is useful in treating it.

guanylate cyclase - Traduction en français - exemples anglais | Reverso Conte

Traductions en contexte de "guanylate cyclase" en anglais-français avec Reverso Context : ... an inhibitor of angiotensin converting enzyme (ACE) are useful for treating a cardiovascular or metabolic disorder, in particular hypertension or diabetes. cyclase de ...

Guanylate Cyclase Activity and Sperm Function | Endocrine Reviews | Oxford Academ

In species with external fertilization, the guanylate cyclase family is responsible for the long-distance interaction between gametes, as its activat ...

Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders by Synergy Pharmaceuticals .

Get details on patent AU2009270833 - Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders by Synergy ...

Soluble Guanylate Cyclase Stimulators and Activators | SpringerLi

Data from research using stimulator and activator families of sGC agonists have provided support for the thesis that sGC bioactivity is ... the so-called SOCRATES trials (SOluble guanylate Cyclase stimulatoR in heArT failure), were conducted in chronic heart ...

Soluble guanylate cyclase stimulation: an emerging option in pulmonary hypertension therapy | European Respiratory Socie

Riociguat is an oral stimulator of the NO receptor soluble guanylate cyclase. It synergises with NO and has demonstrated vasodilatory and antiremodelling properties in preclinical studies. Riociguat has been shown to have a favourable safety profile in healthy ...

SYNERGY PHARMACEUTICALS, INC., Patent Owner, NEW YORK,

View SYNERGY PHARMACEUTICALS, INC.'s, NEW YORK, NY, patent portfolio profile on Patent Buddy. ... 9814752 Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity ...

Oral treatment with plecanatide or dolcanatide attenuates visceral hypersensitivity via activation of guanylate cyclase-C in rat models - CO

Oral treatment with plecanatide or dolcanatide attenuates visceral hypersensitivity via activation of guanylate cyclase-C in rat models By Anusha Thadi, Catherine Beaufrand, Viren Patwa, Apoorva Joshi, John A ...

GLUCOSIDOS CARDIOTONICOS P

Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor glucossidos. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases.

Guanylyl cyclase-C | Transmembrane guanylyl cyclases | IUPHAR/BPS Guide to PHARMACOLO

(2010) Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit. ...

CA2730603A1 - Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders .

The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in ...

AU 2009/256156 A1 - Agonists Of Guanylate Cyclase Useful For The Treatment Of Gastrointestinal Disorders, Inflammation, Cancer And Other Disorders .

What is The Lens Release Notes Lens Use Cases Lens News Policies Our Software Patents Search & Analysis Scholarly Works ... Agonists Of Guanylate Cyclase Useful For The Treatment Of Gastrointestinal Disorders, Inflammation, Cancer And Other 17 0 ...

CA2930674A1 - Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders .

CA2930674A1 - Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders - Google Patents Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation ...

API SYNTHESIS INTERNATIONAL: PRANIDIPI

Pranidipine is a calcium channel blocker. It is a long acting calcium channel antagonist of the dihydropyridine group. PATENT ... Agonists of Guanylate Cyclase Useful For the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders [] ...

PHARM CH 21 (1) - Learning tools & flashcards, for free | Quizl

Why are long-acting beta-adrenergic agonists not useful during an actual acute asthma attack? a. They are likely to cause allergies. b. They need time to build up an effect. c. ...

List of new Gastrointestinal Cancer patents & technologi

Gastrointestinal Cancer - full listing of recent patents, inventions and new technologies and a free subscription to track new patents related to Gastrointestinal Cancer ... Electric Vehicle Patent Pack (PDFs) Research the latest Electric Vehicle inventions